Role of Lactium™ in Psychodermatology: The CERTAIN Trial^# on Patients with Acne Vulgaris

Table 1

Baseline characteristics.

	Group A (Nixiyax plus standard of care) (N = 45)	Group B (standard of care) (N = 40)	-value
Mean age (in years)	22.56 ± 3.19	21.80 ± 3.40	0.2958
Sex, n (%)
Female	28 (0.33%)	24 (0.19%)	0.8338
Male	17 (0.20%)	16 (0.28%)
Serum cortisol levels (μg/dL)	26.92 ± 5.85	27.21 ± 5.08	0.8090
PSS score	21.98 ± 2.66	21.50 ± 2.52	0.3978
HAM-A score	27.20 ± 3.32	27.35 ± 3.08	0.8294
Total acne lesion count	20.9 ± 6.27	22.6 ± 6.28	0.2125
Inflammatory acne lesion count	5.96 ± 2.5	6.95 ± 3.07	0.1082
Noninflammatory acne lesion count	14.98 ± 4.97	15.73 ± 4.49	0.4688
IGA acne severity scale score	2.67 ± 0.67	2.73 ± 0.64	0.6836
DLQI score	13.73 ± 2.07	13.78 ± 1.85	0.9221

N, number of patients; PSS, Perceived Stress Scale; HAM-A, Hamilton Anxiety Rating Scale; IGA, Investigator’s Global Assessment; DLQI, Dermatology Life Quality Index. Pearson’s chi-square test was used to determine the relationship between sex and groups. The -value was calculated using an independent t-test.