Comparative Efficacy Study Combination of Oral Methotrexate and Prednisolone versus Oral Methotrexate in Patients with Lichen Planopilaris

Table 2

Categorical background characteristics of participants by intervention groups.

	Methotrexate N  =  14	Combined therapy N  =  14	Value
Cutaneous involvement	3 (21.4)	2 (14.2)	0.622
Telangiectasia	4 (28.5)	3 (21.4)	0.663
Frontal fibrosing alopecia	1 (7.14)	2 (14.2)	0.541
Facial papules	0	1 (7.14)	0.309
Mucosal involvement	1 (7.14)	1 (7.14)	1.00
Nail involvement	0	0	1.00
Eyebrow involvement	1 (7.14)	0	0.309
Follicular lichen planus	0	0	1.00
Pruritus, mean ± SD	1.07 (0.29)	2.00 (0.30)	0.49
Pain, mean ± SD	0.57 (0.20)	0.36 (0.17)	0.42
Soreness, mean ± SD	0.71 (0.27)	0.50 (0.17)	0.50
zPFE, mean ± SD	1.93 (0.27)	1.71 (0.17)	0.54
PFS, mean ± SD	1.29 (0.29)	1.36 (0.25)	0.85
Pull test, mean ± SD	0.36 (0.13)	0.43 (0.14)	0.71
Spreading, mean ± SD	1.7 (0.1)	2.0 (0.0)	0.17
Erythema, mean ± SD	1.64 (0.29)	1.07 (0.27)	0.15
FK, mean ± SD	1.86 (0.25)	1.93 (0.20)	0.82
PFP, mean ± SD	0.50 (0.20)	0.71 (0.27)	0.52
Initial involvement
Parietal	11 (78.5)	11 (78.5)	1.00
Frontal	0	2 (14.2)	0.142
Temporal	0	1 (7.14)	0.309
Occipital	1 (7.14)	1 (7.14)	1.00
Mixed	2 (14.2)	2 (14.2)	1.00

PFE, perifollicular erythema; PFS, perifollicular scaling; FK, follicular keratosis.