Research Article
Gene Expression of CD70 and CD27 Is Increased in Alopecia Areata Lesions and Associated with Disease Severity and Activity
Table 2
Clinical data of patients with AA (n = 44).
| Clinical data | No. | % |
| Duration of AA lesions (months) | <3 months | 8 | 20.0 | 3–12 months | 11 | 27.5 | 12–24 months | 5 | 12.5 | 2–5 years | 9 | 22.5 | ≥5 years | 7 | 17.5 | Min.–Max. | 0.25–168.0 | Mean ± SD | 26.98 ± 39.75 | Median (IQR) | 12.0 (3.0–36.0) | Course | Progressive | 27 | 67.5 | Fluctuating | 5 | 12.5 | Stationary | 8 | 20.0 | Age of disease onset (years) | Children (0- <13) | 6 | 15.0 | Adolescents and young youth (13- <25) | 16 | 40.0 | Adulthood (25- <40) | 10 | 25.0 | Middle age (40- <60) | 8 | 20.0 | Min.–Max. | 2.0–50.0 | Mean ± SD | 25.58 ± 13.25 | Median (IQR) | 24.0 (17.0–32.0) | Alopecia in other sites (beard or eyebrows) | 14 | 35.0 | SALT score | S1 (<25% hair loss) | 22 | 55.0 | S2 (25–49% hair loss) | 9 | 22.5 | S3 (50–74% hair loss) | 7 | 17.5 | S4 (75–99% hair loss) | 0 | 0.0 | S5 (100% hair loss) | 2 | 5.0 | Min.–Max. | 1.50–100.0 | Mean ± SD | 25.08 ± 26.02 | Median (IQR) | 12.0 (3.0–42.0) | Pattern | Patchy | 22 | 55.0 | Single patch | 7 | 17.5 | Multiple separate patches | 12 | 30.0 | Multiple reticular patches | 3 | 7.5 | Ophiasis ± other patterns | 16 | 40.0 | Ophiasis | 8 | 20.0 | Multiple separate patches and ophiasis | 7 | 17.5 | Ophiasis and sisaipho | 1 | 2.5 | Universalis | 2 | 5.0 | Previous attacks of AA | 22 | 55.0 | Family history of AA | 3 | 7.5 | Family history of atopy | 5 | 12.5 | Family history of autoimmune disorders | 3 | 7.5 | Nail changes (pitting, ridging, dystrophy) | 7 | 17.5 | Black dots | 30 | 75.0 | Broken hairs | 16 | 40.0 | Tapering hairs | 26 | 65.0 | Positive hair pull test | 22 | 55.0 |
|
|
SD: standard deviation; IQR: interquartile range. AA: alopecia areata; SALT : Severity of Alopecia Tool.
|