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Major features (3 of 4 required) |
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(1) Pruritus |
(2) Typical morphology and distribution |
(2.1) flexural lichenification or linearity in adults |
(2.2) facial and extensor involvement in infants and children |
(3) Chronic or chronically relapsing dermatitis |
(4) Personal or family history of atopy, such as asthma, allergic rhinitis, and atopic dermatitis |
Minor features (3 of 23 required) |
(1) Xerosis |
(2) Ichthyosis/palmar hyperlinearity/keratosis pilaris |
(3) Immediate (type 1) skin test reactivity |
(4) Elevated serum immunoglobulin E |
(5) Early age of onset |
(6) Tendency toward cutaneous infections (S. aureus and herpes simplex virus)/impaired, cell-mediated immunity |
(7) Tendency toward nonspecific hand or foot dermatitis |
(8) Nipple eczema |
(9) Chelitis |
(10) Recurrent conjunctivitis |
(11) Dennie-morgan infraorbital fold |
(12) Keratoconus |
(13) Anterior subcapsular cataract |
(14) Orbital darkening |
(15) Facial pallor/facial erythema |
(16) Pityriasis alba |
(17) Anterior neck fold |
(18) Itch when sweating |
(19) Intolerance to wool and lipid solvents |
(20) Perifollicular accentuation |
(21) Food intolerance |
(22) Course influence by environmental/emotional factors |
(23) White dermographism/delayed blanch |
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