|
| Major features (3 of 4 required) |
|
| (1) Pruritus |
| (2) Typical morphology and distribution |
| (2.1) flexural lichenification or linearity in adults |
| (2.2) facial and extensor involvement in infants and children |
| (3) Chronic or chronically relapsing dermatitis |
| (4) Personal or family history of atopy, such as asthma, allergic rhinitis, and atopic dermatitis |
| Minor features (3 of 23 required) |
| (1) Xerosis |
| (2) Ichthyosis/palmar hyperlinearity/keratosis pilaris |
| (3) Immediate (type 1) skin test reactivity |
| (4) Elevated serum immunoglobulin E |
| (5) Early age of onset |
| (6) Tendency toward cutaneous infections (S. aureus and herpes simplex virus)/impaired, cell-mediated immunity |
| (7) Tendency toward nonspecific hand or foot dermatitis |
| (8) Nipple eczema |
| (9) Chelitis |
| (10) Recurrent conjunctivitis |
| (11) Dennie-morgan infraorbital fold |
| (12) Keratoconus |
| (13) Anterior subcapsular cataract |
| (14) Orbital darkening |
| (15) Facial pallor/facial erythema |
| (16) Pityriasis alba |
| (17) Anterior neck fold |
| (18) Itch when sweating |
| (19) Intolerance to wool and lipid solvents |
| (20) Perifollicular accentuation |
| (21) Food intolerance |
| (22) Course influence by environmental/emotional factors |
| (23) White dermographism/delayed blanch |
|
