Research Article

The Combined Use of Metformin and Methotrexate in Psoriasis Patients with Metabolic Syndrome

Table 3

Treatment results of the study group (n = 35).

After (month)PASI (before treatment) (X ± SD)PASI (after treatment) (X ± SD)% Reduction

121.8 ± 8.316.9 ± 7.722.480.01
214.3 ± 7.434.400.0002
39.0 ± 8.558.72<0.001

Note. Mean PASI decreased each month. After three months of treatment, the mean PASI dropped by 58.72%. There was a statistically significant difference in PASI before and after treatment (, Student t-test).