Prescribing Antidepressants and Benzodiazepines in the Netherlands: Is Chronic Physical Illness Involved?

Table 2

Odds ratios (95% confidence interval (CI)) of receiving at least one benzodiazepines or antidepressant prescription in 1999, analysed separately for men and women and for persons younger and older than 65.

Odds ratio* (95% CI) of at least one benzodiazepines prescription			Odds ratio* (95% CI) of at least one antidepressants prescription
	Men	Women	Men	Women
	(14.1% of 306,129	(25.0% of 428,619	(4.5% of 306,129	(7.8% of 428,619
	with prescription)	with prescription)	with prescription)	with prescription)
Reference	1.00	1.00	1.00	1.00
Diabetes	1.16 (1.07–1.26)	1.14 (1.07–1.21)	1.31 (1.15–1.49)	1.24 (1.13–1.37)
Pulmonary	1.85 (1.76–1.95)	1.91 (1.83–1.99)	1.37 (1.25–1.51)	1.43 (1.34–1.53)
Cardiovascular	1.73 (1.69–1.78)	1.66 (1.63–1.69)	1.48 (1.42–1.54)	1.36 (1.33–1.40)
Multimorbidity	2.17 (2.09–2.26)	1.87 (1.82–1.92)	1.80 (1.69–1.93)	1.53 (1.46–1.60)
	<65 years	>=65 years	<65 years	>=65 years
	(17.8% of 487,546	(25.7% of 247,202	(6.8% of 487,546	(5.8% of 247,202
	with prescription)	with prescription)	with prescription)	with prescription)
Reference	1.00	1.00	1.00	1.00
Diabetes	1.17 (1.09–1.24)	1.13 (1.05–1.21)	1.35 (1.23–1.48)	1.11 (0.98–1.26)
Pulmonary	1.97 (1.89–2.04)	1.73 (1.63–1.83)	1.52 (1.43–1.62)	1.13 (1.01–1.26)
Cardiovascular	1.72 (1.69–1.75)	1.65 (1.61–1.68)	1.50 (1.46–1.55)	1.23 (1.18–1.28)
Multimorbidity	2.15 (2.07–2.22)	1.85 (1.79–1.91)	1.83 (1.74–1.93)	1.37 (1.29–1.44)

^∗Odds ratio adjusted for age and sex.