Prescribing Antidepressants and Benzodiazepines in the Netherlands: Is Chronic Physical Illness Involved?

Table 3

Hazard ratios (95% confidence interval (CI)) of benzodiazepines or antidepressant prescriptions in 2000-2004 for those without such prescriptions in 1999.

Benzodiazapines				Antidepressants
	N	Cumulative incidence	Hazard ratio*	N	Cumulative incidence	Hazard ratio*
		(%)	(95% CI)		(%)	(95% CI)
Reference	390,050	25.1	1.00	439,658	9.3	1.00
Diabetes	8,990	26.3	1.08 (1.04–1.13)	10,384	11.1	1.25 (1.18–1.33)
Pulmonary	15,357	33.5	1.45 (1.41–1.49)	19,306	13.4	1.52 (1.46–1.58)
Cardiovascular	139,157	29.5	1.23 (1.22–1.25)	177,237	10.5	1.17 (1.14–1.19)
Multimorbidity	584,439	32.1	1.37 (1.34–1.40)	40,835	13.2	1.50 (1.46–1.55)

^∗Hazard ratio adjusted for age and sex.