General characteristics of the three databases.
|Period of study||November 97||Septembert 98||February 01|
|February 98||January 99||July 01|
|Objective of the study||Assess efficacy, onset of effect, and tolerance to mirtazapine in the treatment of major depression||Assess the efficacy and tolerance to mirtazapine in sleep and anxiety in major depression||Evaluate the clinical evolution of depression and somatic symptoms during the first three months of treatment with mirtazapine |
|Number of psychiatrists||300||150||100|