Depression Research and Treatment / 2011 / Article / Tab 1

Research Article

Efficacy of Chronic Antidepressant Treatments in a New Model of Extreme Anxiety in Rats

Table 1

Effects of subchronic fluoxetine (FLX) treatment (5 mg/kg/21 d, IP, , median with limits of interquartile range values). Mann-Whitney U test: * ; ** (FLX versus Vehicle). Wilcoxon-test: # (test versus baseline). Data were expressed as median with limits of interquartile range values.

MeasuresBaseline (before treatment)Test (after treatment)
Vehicle ( )FLX ( )Vehicle ( )FLX ( )

Number of jumps23 (9.8–37.3)21 (16.5–31.5)22 (10.5–27)9*# (0–12.8)
Latency before the first jump (s)15 (11.3–21.5)14 (11.8–23.3)16 (12.3–18)27*# (16.3–90)
Immobility (s)140 (126.8–144.8)59 (33.3–93.8)164# (140–176.8)70** (58.8–115)