Depression Research and Treatment / 2011 / Article / Tab 2

Research Article

Efficacy of Chronic Antidepressant Treatments in a New Model of Extreme Anxiety in Rats

Table 2

Effects of subchronic imipramine (IMI) treatment (10 mg/kg/14 d, IP, , median with limits of interquartile range values). Mann-Whitney U test: * ; ** (IMI versus vehicle). Wilcoxon-test: # (test versus baseline). Data were expressed as median with limits of interquartile range values.

MeasuresBaseline (before treatment)Test (after treatment)
Vehicle ( )IMI ( )Vehicle ( )IMI ( )

Number of jumps24 (17.3–29)22 (15.8–25)28 (24.5–32.5)15**# (1.8–18.8)
Latency before the first jump (s)5 (3.3–11)12 (6.3–24.3)10 (7.3–18)22**#   (19.8–74.5)
Immobility (s)107 (93.5–117)103 (93.5–150.8)157#  (124.8–182.5)86*  (33.5–128.5)