Efficacy of Chronic Antidepressant Treatments in a New Model of Extreme Anxiety in Rats

Table 6

Effects of acute fluoxetine (FLX) treatment (10 mg/kg, IP, 𝑛=9, median with limits of interquartile range values). Wilcoxon-test: ^#𝑃<0.05 (test versus baseline). Data are expressed as median with limits of interquartile range values.

Measures	Baseline (before treatment)		Test (after treatment)
	Vehicle (𝑛=9)	FLX (𝑛=9)	Vehicle (𝑛=9)	FLX (𝑛=9)
Number of jumps	17 (13.5–19.5)	15 (13.3–17.8)	19 (16.8–24.8)	21^# (19.0–22.5)
Latency before the first jump (s)	19 (12.8–27.3)	20 (14.8–29.5)	16 (13.0–17.8)	14^# (4.8–19.5)
Immobility (s)	85 (68.0–98.0)	97 (81.5–114.8)	108^# (93.8–126.3)	139^# (115.0–159.3)