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Depression Research and Treatment
Volume 2012, Article ID 670549, 6 pages
Research Article

Social-Cognitive Bias and Depressive Symptoms in Outpatients with Bipolar Disorder

1Department of Psychiatry, Príncipe de Asturias University Hospital, University of Alcalá, Carretera Alcalá-Meco s/n, 28805 Alcalá de Henares, Madrid, Spain
2Department of Psychiatry, Hospital Provincial de Toledo, Plaza de la Merced, 4, 45002 Toledo, Spain

Received 15 September 2011; Accepted 29 November 2011

Academic Editor: Po-See Chen

Copyright © 2012 Guillermo Lahera et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A deficit of social cognition in bipolar disorder has been shown, even when patients are stable. This study compares the attribution of intentions (social-cognitive bias) in a group of 37 outpatients with bipolar disorder with 32 matched control subjects. Bipolar patients scored significantly higher in the Ambiguous Intentions Hostility Questionnaire, showing an angry and intentionality bias ( , ). Differences in blame scale and hostility bias did not reach statistical significance, but a trend was found ( ). Bipolar patients with depressive symptoms presented a higher score in the angry bias scale ( ) and aggressivity bias scale ( ). The global functioning (GAF) correlates significantly with intentionality ( ), angry ( ), and aggressivity ( ) biases. Bipolar patients show a social-cognitive bias that may play a role in their functional outcome.