Spiritual Struggle in Parents of Children with Cystic Fibrosis Increases Odds of Depression

Table 3

Longitudinal multivariable statistical model examining spiritual struggle and other factors related to depression.

Variable	OR	(95% CI)	P
Spiritual struggle
Moderate/severe	15.24	(4.14, 56.02)	0.0003
Mild	1.33	(0.62, 2.82)
None	1
Time point
Baseline	0.15	(0.07, 0.32)	<0.0001
Follow-up	1
Parent gender
Female	2.48	(1.05, 5.90)	0.0397
Male	1
Being “at peace”	0.87	(0.76, 0.99)	0.0419
Child age, in years	0.92	(0.84, 1.01)	0.08

OR, odds ratio; CI, confidence interval. Model also includes adjustment for site, longitudinal correlation, and parent dyad effects (see Materials and Methods). categorical variables, the estimate is the odds of having depression being in the indicator group versus the reference group (labeled by OR = 1). For continuous covariates it is the increase in odds of depression when the covariate increased by 1 unit. value based on Type III Tests of Fixed Effects.