Anxiolytic and Antidepressant Effects of Maerua angolensis DC. Stem Bark Extract in Mice

Table 1

Effects of Maerua angolensis stem bark extract in the Irwin’s test.

Dose (mg kg^-1)	Effects (time period)	D/T
0	No effect (0-180 min)	0/5
100	Analgesia, reduced fear response (60-120 min)	0/5
300	Analgesia, reduced fear response (30-120 min)	0/5
1000	Analgesia, reduced fear and touch response (30-120 min)	0/5
3000	Analgesia, reduced fear, touch response & activity (30-120 min)	0/5
5000	Analgesia, reduced fear, touch response and activity (30-120 min) Increased jumps (15-30 min).	0/5

D= number of deaths recorded T= number of animals treated