Table 2: Comparison of characteristics of type 2 Diabetes Mellitus patients without depressive symptoms vs type 2 Diabetes Mellitus patients with depressive symptoms.

No Depressive symptoms (30)Depressive symptoms (22)p

Age63 ± 1262 ± 120.609
female20 (66. 7%)15 (68. 2%)0.575
BMI (kg/m2)31.3 ± 5.731.2 ± 5.50.919
Current smoking7 (23. 3%)6 (27. 3%)0.757
CAD4 (13. 3%)6 (27. 3%)0.183
Arterial Hypertension22 (73. 3%)13 (59. 1%)0.312
MAP98 ± 1.194 ± 0.90.185
Duration of diabetes (months)108 (57-156)78 (24-240)0.933
Creatinine (mg/dl)0.85 ± 0.170.88 ± 0.20.620
MDRD79 ± 2077 ± 170.595
LDL (mg/dl)110 (85-123)112 (75-130)0.945
HDL (mg/dl)45 ± 1351 ± 160.133
Triglycerides (mg/dl)145 (109-192)121 (92-182)0.394
HbA1c (%)7.1 ± 1.37.0 ± 0.80.895
TNFa (pg/ml)5.3 ± 2.06.6 ± 2.60.058
S100-B (pg/ml)2.1 (1.9-10.9)2.4 (1.9-14.8)0.637
Insulin4 (13. 3%)6 (27. 3%)0.290
Metformin22 (73. 3%)14 (63. 6%)0.548
DPP4 inhibitors5 (16. 7%)7 (31. 8%)0.171
Sulphonylureas10 (33. 3%)4 (18. 1%)0.185
ACE/ARBs16 (71. 5%)11 (50%)0.814
b-blockers10 (33. 3%)8 (36. 4%)0.820
Antiplatelet treatment9 (30%)8 (36. 4%)0.767
Statin treatment16 (53. 3%)12 (54. 5%)0.931
Zung self-assessment score37 ± 953 ± 4<0.001
Hamilton (interview) rating scale score (17)9 (8-10)3 (2-5)<0.001

BMI: body mass index, TIA: transient ischemic attack, CAD: cardiovascular disease, MAP: mean arterial pressure (MAP = [(2 x diastolic)+systolic]/3, MDRD: GFR (mL/min/1.73 m2) = 175 × (Scr)-1.154 × (Age)-0.203 × (0.742 if female) (mL/min/1.73 m2), LDL: low density lipoprotein, HDL: high density lipoprotein, HbA1c: glycated hemoglobin, TNFa: tumor necrosis factor a, S100B: S100 calcium binding peptide b, DPP4 inhibitors: dipeptidyl-peptidase 4 inhibitors, ACE: angiotensin-converting-enzyme inhibitor, and ARBs: angiotensin receptor blockers.