Table of Contents Author Guidelines Submit a Manuscript
Evidence-Based Complementary and Alternative Medicine
Volume 3, Issue 2, Pages 261-265
http://dx.doi.org/10.1093/ecam/nel010
Original Article

Antimicrobial Activity of Indigofera suffruticosa

1Departamento de Histologia e Embriologia do Centro de Ciências Biológicas da Universidade Federal de Pernambuco, Recife-PE, Brazil
2Mestrando em Patologia Geral do Centro de Ciências da Saúde da Universidade Federal de Pernambuco, Recife-PE, Brazil
3Doutoranda em Nutrição do Centro de Ciências da Saúde da Universidade Federal de Pernambuco, Recife-PE, Brazil
4Departamento de Bioquímica do Centro de Ciências Biológicas da Universidade Federal de Pernambuco, Recife-PE, Brazil
5Departamento de Centro de Ciências Biológicas da Universidade Federal de Pernambuco, Recife-PE, Brazil
6Departamento de Ciências Farmacêutica do Centro de Ciências da Saúde da Universidade Federal da Paraíba João, Pessoa-PB, Brazil

Received 22 March 2005; Accepted 8 February 2006

Copyright © 2006 Sônia Pereira Leite et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Various organic and aqueous extracts of leaves of Indigofera suffruticosa Mill (Fabaceae) obtained by infusion and maceration were screened for their antibacterial and antifungal activities. The extracts were tested against 5 different species of human pathogenic bacteria and 17 fungal strains by the agar-solid diffusion method. Most of the extracts were devoid of antifungal and antibacterial activities, except the aqueous extract of leaves of I. suffruticosa obtained by infusion, which showed strong inhibitory activity against the Gram-positive bacteria Staphylococcus aureus with a minimal inhibitory concentration (MIC) of 5000 µg ml−1. The MIC values to dermatophyte strains were 2500 µg ml−1 against Trichophyton rubrum (LM-09, LM-13) and Microsporum canis. This study suggests that aqueous extracts of leaves of I. suffruticosa obtained by infusion can be used in the treatment of skin diseases caused by dermatophytes.