Evidence-Based Complementary and Alternative Medicine

Evidence-Based Complementary and Alternative Medicine / 2006 / Article

Review Article | Open Access

Volume 3 |Article ID 854543 | https://doi.org/10.1093/ecam/nel021

Yamni Nigam, Alyson Bexfield, Stephen Thomas, Norman Arthur Ratcliffe, "Maggot Therapy: The Science and Implication for CAM Part I—History and Bacterial Resistance", Evidence-Based Complementary and Alternative Medicine, vol. 3, Article ID 854543, 5 pages, 2006. https://doi.org/10.1093/ecam/nel021

Maggot Therapy: The Science and Implication for CAM Part I—History and Bacterial Resistance

Received13 Sep 2005
Accepted23 Mar 2006


It is now a universally acknowledged fact that maggot therapy can be used successfully to treat chronic, long-standing, infected wounds, which have previously failed to respond to conventional treatment. Such wounds are typically characterized by the presence of necrotic tissue, underlying infection and poor healing. Maggot therapy employs the use of freshly emerged, sterile larvae of the common green-bottle fly, Phaenicia (Lucilia) sericata, and is a form of artificially induced myiasis in a controlled clinical situation. In this review article, we will discuss the role of maggots and their preparation for clinical use. Maggot therapy has the following three core beneficial effects on a wound: debridement, disinfection and enhanced healing. In part I we explore our current understanding of the mechanisms underlying these effects.

Copyright © 2006 Yamni Nigam et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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