Review | Open Access
Preeti Chavan, Kalpana Joshi, Bhushan Patwardhan, "DNA Microarrays in Herbal Drug Research", Evidence-Based Complementary and Alternative Medicine, vol. 3, Article ID 945498, 11 pages, 2006. https://doi.org/10.1093/ecam/nel075
DNA Microarrays in Herbal Drug Research
Natural products are gaining increased applications in drug discovery and development. Being chemically diverse they are able to modulate several targets simultaneously in a complex system. Analysis of gene expression becomes necessary for better understanding of molecular mechanisms. Conventional strategies for expression profiling are optimized for single gene analysis. DNA microarrays serve as suitable high throughput tool for simultaneous analysis of multiple genes. Major practical applicability of DNA microarrays remains in DNA mutation and polymorphism analysis. This review highlights applications of DNA microarrays in pharmacodynamics, pharmacogenomics, toxicogenomics and quality control of herbal drugs and extracts.
Copyright © 2006 Preeti Chavan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.