Hepatoprotective Effects of Orthosiphon stamineus Extract on Thioacetamide-Induced Liver Cirrhosis in Rats
Table 1
The body, liver, and spleen weight of rats after two-month treatments.
Animal group
Body weight (g) (BW)
Liver weight (g) (LW)
LW/BW (%)
Spleen weight (g) (SW)
SW/BW (%)
Normal control
254.9 ± 28.69
6.71 ± 0.64
2.71 ± 0.18
0.47 ± 0.08
0.18 ± 0.02
TAA control (hepatotoxic group)
202.0 ± 19.10
11.00 ± 1.11*a
5.43 ± 0.17*a
0.52 ± 0.07
0.26 ± 0.03
HD 200 mg/kg (treatment group)
232.7 ± 16.12
10.43 ± 0.69
4.50 ± 0.19*b
0.54 ± 0.04
0.23 ± 0.01
LD 100 mg/kg (treatment group)
263.3 ± 8.53
10.43 ± 0.72
3.94 ± 0.16**c
0.55 ± 0.03
0.21 ± 0.01
Silymarin 50 mg/kg (hepatoprotective group)
257.0 ± 21.97
7.71 ± 2.78
2.94 ± 0.13**c
0.53 ± 0.07
0.20 ± 0.01
All values are expressed as mean ± S.E.M. Means with different superscripts are significantly different.
a versus Normal control group, b versus TAA control group, and c versus TAA control group.
