Genetic Effects of FTO and MC4R Polymorphisms on Body Mass in Constitutional Types
Figure 1
The LD (a) and haplotype (b) structures
of FTO were determined via Haploview
program. In FTO haplotypes, blue and
red colors indicate major and minor alleles of each SNP,
while thick and thin lines between blocks indicate >10%
and >1% connecting frequencies, respectively, between
haplotypes in neighboring blocks (b). (c) Among the 14 SNPs
previously reported to reside in the first intron of FTO,
three, two and eight SNPs are located in block 1 (bl1), block 2 (bl2) and
block 3 (bl3), respectively.