Genetic Effects of FTO and MC4R Polymorphisms on Body Mass in Constitutional Types
Table 1
Anthropometric and clinical characteristics of the subjectsa.
Feature
All
TE
SY
SE
-value*
Kirin population
Number (n)
835
685
81
69
—
Female (%)
93.4
92.1
98.8
100
—
Age (years)
27.7 ± 8.09
27.7 ± 8.01
28.8 ± 9.54
27.0 ± 6.93
.39
BMI (kg/m2)
26.5 ± 4.66
27.2 ± 4.63
23.6 ± 3.48
23.0 ± 3.19
8.1 × 10-20
WHR
0.888 ± 0.0755
0.897 ± 0.0759
0.849 ± 0.0578
0.840 ± 0.0549
2.4 × 10-14
BMI loss (%)a
−7.86 ± 4.10 (538)
−8.12 ± 3.98 (443)
−5.74 ± 4.55 (48)
−7.55 ± 4.16 (47)
5.4 × 10-4
WHR loss (%)a
−3.12 ± 2.52 (538)
−3.32 ± 2.45 (443)
−1.87 ± 2.46 (48)
−2.54 ± 2.82 (47)
1.7 × 10-4
Multicenter population
Number (n)
535
196
172
137
—
Female (%)
64.2
57.1
70.9
66.9
—
Age (years)
42.6 ± 13.1
43.7 ± 13.9
43.0 ± 12.1
41.1 ± 12.9
.18
BMI (kg/m2)
22.9 ± 3.09
25.0 ± 2.95
22.4 ± 2.54
20.9 ± 2.01
2.8 × 10-30
WHR
0.885 ± 0.0736
0.915 ± 0.0632
0.876 ± 0.0671
0.858 ± 0.0806
5.0 × 10-11
The values are given as mean ± SD; aThe percentage of a loss in body mass was calculated as one-hundredth of the value of body mass change after the weight-control program divided by the value before the program. The number of subjects participated in the program are indicated in parentheses; *The -value (, boldface) was calculated with analysis of variance.