Original Article
Efficacy and Safety Assessment of T. Angelica Herbal Tonic, a Phytomedicinal Product Popularly Used in Nigeria
Table 3
Summary of reproductive effects of TAHT in experimental rats.
| Parameter | Control group | Test group |
| Number of virgin rats | 5 | 5 | Percentage of pregnancy at the end of experiment | 80 | 80 | Percentage of pregnant by the 43rd day | 0 | 80 | Percentage of pregnant by the 65th day | 80 | 80 | Mean number of days elapsed before delivery | 55.00 ± 4.71 | 31.25 ± 4.52* | Total litter size | 21 | 30 | Average litter size | 5.25 ± 0.95 | 7.50 ± 0.50 | Number of male litters | 10 | 16 | Number of female litters | 11 | 14 | Average birth weight (g) | 5.95 ± 0.10 | 4.81 ± 0.19* | Percentage increase in weight 21 days after birth | 364.53 ± 10.01 | 390.74 ± 34.47 |
| Percent weight of major organs (relative to body weight)
| (i) Heart | 0.463 ± 0.024 | 0.358 ± 0.017* | (ii) Kidney | 0.639 ± 0.037 | 0.595 ± 0.020 | (iii) Lung | 0.646 ± 0.020 | 0.750 ± 0.022 | (iv) Spleen | 0.297 ± 0.024 | 0.304 ± 0.008 | (v) Liver | 5.185 ± 0.147 | 4.17 ± 0.152* |
| Duration of pregnancy (days) in each of the four pregnancies achieved in both groups (counting from the start of mating)
| (i) First animal | 46 | 21 | (ii) Second animal | 48 | 30 | (iii) Third animal | 61 | 31 | (iv) Fourth animal | 65 | 43 |
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*Significant P < .05 versus control.
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