Efficacy and Safety Assessment of T. Angelica Herbal Tonic, a Phytomedicinal Product Popularly Used in Nigeria

Table 3

Summary of reproductive effects of TAHT in experimental rats.

Parameter	Control group	Test group
Number of virgin rats	5	5
Percentage of pregnancy at the end of experiment	80	80
Percentage of pregnant by the 43rd day	0	80
Percentage of pregnant by the 65th day	80	80
Mean number of days elapsed before delivery	55.00 ± 4.71	31.25 ± 4.52*
Total litter size	21	30
Average litter size	5.25 ± 0.95	7.50 ± 0.50
Number of male litters	10	16
Number of female litters	11	14
Average birth weight (g)	5.95 ± 0.10	4.81 ± 0.19*
Percentage increase in weight 21 days after birth	364.53 ± 10.01	390.74 ± 34.47
Percent weight of major organs (relative to body weight)
(i) Heart	0.463 ± 0.024	0.358 ± 0.017*
(ii) Kidney	0.639 ± 0.037	0.595 ± 0.020
(iii) Lung	0.646 ± 0.020	0.750 ± 0.022
(iv) Spleen	0.297 ± 0.024	0.304 ± 0.008
(v) Liver	5.185 ± 0.147	4.17 ± 0.152*
Duration of pregnancy (days) in each of the four pregnancies achieved in both groups (counting from the start of mating)
(i) First animal	46	21
(ii) Second animal	48	30
(iii) Third animal	61	31
(iv) Fourth animal	65	43

*Significant P < .05 versus control.