Anti-Hyperglycemic Properties of Crude Extract and Triterpenes from Poria cocos
Figure 3
Glucose-lowering effects of the crude extract of P. cocos and triterpenes in STZ-treated mice. C57BL mice, which have received a high dose of STZ, were tube-fed with water (Ctr), glimepiride (GLM: 2.5 mg/kg BW), metformin (Met: 60 mg/kg BW), crude extract (CE: 10, 50, or 100 mg/kg BW), dehydrotumulosic acid (DHTuA: 1, 5, or 10 mg/kg BW), dehydrotrametenolic acid (DHTA: 1, 5, and 10 mg/kg BW), and pachymic acid (PA: 1, 5, or 10 mg/kg). Blood glucose levels were measured before ( and 0 h) and after (1 to 4 h) tube feeding and injection of insulin 2.5 IU/kg BW. All the above data are expressed as P; () indicates the difference between control (Ctr) and experimental group. The mouse number () is indicated in parenthesis.
