[Retracted] Protective Effects of Rosa damascena and Its Active Constituent on Aβ(25–35)-Induced Neuritic Atrophy
Figure 5
Protective effect of compound 1 on Aβ(25–35)-induced dendritic atrophy. Cortical neurons were cultured for three days and were then treated with (Veh) or without 10 μM Aβ(25–35) (Cont). Cells were simultaneously treated by compound 1 (1 μM), subfraction F-4 (5 μg/mL), DHA (1 μM), NGF (100 ng/mL) or vehicle (0.1% DMSO, Veh). Five days after treatment, the cells were fixed and immunostained for MAP2a&2b. The lengths of MAP2a&2b-positive neurites were measured. Values are means ± SE of data from four areas. *P < 0.05 versus Aβ(25–35)/Veh (Student's t-test). Typical photographs were shown.
