Royal Jelly Facilitates Restoration of the Cognitive Ability in Trimethyltin-Intoxicated Mice

Figure 3

Amelioration by RJ of the TMT-induced damage to the hippocampal DG. (A) Photographs of Nissl-stained hippocampal DG of mice 8 days after PBS (a), or TMT (b) treatment, or TMT treatment + 6-day feeding of 5% RJ diet (c). Scale bar: 50 𝜇m. (B) Number of granule cells in the hippocampal DG of mice 8 days after PBS (a), or TMT treatment (b), or TMT treatment + 6-day feeding of 5% RJ diet (c). The values are expressed as the mean ± SE (n = 4). The difference between the control value (PBS-treated mice fed without RJ) and that for TMT-treated mice fed without RJ diet was significant at **P <  .01 by Tukey's test. ^##P <  .01, TMT-treated mice with versus without RJ.