The Aqueous Soluble Polyphenolic Fraction of <i>Psidium guajava</i> Leaves Exhibits Potent Anti-Angiogenesis and Anti-Migration Actions on DU145 Cells

<table>Action mechanism of the aqueous extract of PE on the DU145 cell line. The cell viability was prominently suppressed by PE. The angiogenesis was inhibited by PE through the downregulation of VEGF, IL-6 and IL-8. The cell migration was found inhibited through downregulation of MMP-2, MMP-9 and TIMP-2.</table>

Evidence-Based Complementary and Alternative Medicine

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Figure 7

Figure 7: The Aqueous Soluble Polyphenolic Fraction of <i>Psidium guajava</i> Leaves Exhibits Potent Anti-Angiogenesis and Anti-Migration Actions on DU145 Cells 

Figure 7 | The Aqueous Soluble Polyphenolic Fraction of Psidium guajava Leaves Exhibits Potent Anti-Angiogenesis and Anti-Migration Actions on DU145 Cells 