Research Article
Immunohistochemical Evaluation of p63, E-Cadherin, Collagen I and III Expression in Lower Limb Wound Healing under Honey
Table 1
ANOVA in evaluating E-cadherin, Collagen I and III intensity differences within and between the study classes and assessment of collagen ratios.
| | Molecule of interest | Study groups | | | NP1 | NP2 | NP3 |
BP1 | BP2 | BP3 | A15P1 | A15P2 | A15P3 | A22P1 | A22P2 | A22P3 |
| | E-cadherin | Mean (Sd) | 6.64 (0.99) | 9.00 (1.04) | 9.16 (0.94) | 5.16 (1.18) | 4.24 (1.45) | 4.12 (1.99) | 7.08 (1.35) | 9.32 (1.14) | 7.88 (1.13) | 5.88 (1.20) | 8.60 (1.47) | 8.36 (1.29) | | value within study gr. | 50.39* | 3.263* | 21.90* | 32.29* | | value between study gr. | | | | 89.07* |
| | Collagen I | Mean (Sd) | 4.48 (1.16) | 4.84 (1.14) | 4.44 (1.73) | 9.68 (0.63) | 9.36 (0.7) | 7.84 (0.72) | 8.76 (0.93) | 7.64 (1.44) | 6.68 (1.38) | 4.68 (1.07) | 5.04 (1.54) | 4.84 (2.12) | | value within study gr. | 0.64* | 40.87* | 16.85* | 0.31* | | value between study gr. | | | | 173* |
| | Collagen III | Mean (Sd) | 4.44 (0.87) | 4.44 (0.87) | 2.16 (1.03) | 6.88 (1.13) | 5.68 (1.07) | 4.60 (1.35) | 6.16 (1.205) | 4.92 (1.08) | 4.41 (0.92) | 4.48 (0.87) | 4.28 (0.84) | 2.31 (1.11) | | value within study gr. | 50.57* | 22.94* | 39.10* | 39.62* | | value between study gr. | | | | 34.40* |
| | Collagen ratio (I/III) | 1.25 | 1.57 | 1.49 | 1.31 |
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*
value <.0001, N-Normal skin, B-Before intervention of honey, A15-15 days after intervention and A22-22 days after intervention.
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