Research Article

Suppressive Effect on Lipopolysaccharide-Induced Proinflammatory Mediators by Citrus aurantium L. in Macrophage RAW 264.7 Cells via NF- B Signal Pathway

Figure 6

Suppressive effects of CME on the LPS-induced protein expression of COX-2 and iNOS in RAW 264.7 cells. RAW 264.7 cells were pretreated with CME for 1 hour, and then incubated with LPS for 18 hours. The cells were lysed, and the lysates were examined by immunoblotting for the protein of (a) COX-2 and (b) iNOS. * indicates an increase in protein expression relative to the control ( ), ** indicates a decrease in protein expression relative to the LPS group ( ).
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(a)
248592.fig.006b
(b)