Gastroprotective Effect of Ginger Rhizome (Zingiber officinale) Extract: Role of Gallic Acid and Cinnamic Acid in H+, K+-ATPase/H. pylori Inhibition and Anti-Oxidative Mechanism

<table class="table-group" id="tab6"><tr><td><table class="table"><tr><td class="thead-hr" colspan="5"><hr/></td></tr><tr class="thead"><td align="left">GRAE</td><td align="center">Phenolics (mg g−1)</td><td align="center">AOX (% contribution)</td><td align="center">PPI (% contribution)</td><td align="center">H pylori-inhibition (% contribution)</td></tr><tr><td class="thead-hr" colspan="5"><hr/></td></tr><tr><td align="left">Gallic acid</td><td align="center">3.4</td><td align="center">93</td><td align="center">9</td><td align="center">66</td></tr><tr><td align="left">Cinnamic acid</td><td align="center">3.8</td><td align="center">1</td><td align="center">88</td><td align="center">30</td></tr><tr><td align="left">Other phenolics</td><td align="center">0.4</td><td align="center">6</td><td align="center">3</td><td align="center">4</td></tr><tr class="table-tr"><td colspan="5"><hr class="tbody-hr"/></td></tr></table></td></tr><tr class="table-fn"><td>Gallic acid significantly contributed to anti-oxidant activity than cinnamic acid where as cinnamic acid contributed to H+, K+-ATPase inhibition. </td></tr></table>

Relative percentage contribution of individual phenolic acids towards anti-oxidant, anti-H. pylori and H+, K+-ATPase inhibition.

Evidence-Based Complementary and Alternative Medicine

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Table 6

Table 6: Gastroprotective Effect of Ginger Rhizome (Zingiber officinale) Extract: Role of Gallic Acid and Cinnamic Acid in H+, K+-ATPase/H. pylori Inhibition and Anti-Oxidative Mechanism

Table 6 | Gastroprotective Effect of Ginger Rhizome (Zingiber officinale) Extract: Role of Gallic Acid and Cinnamic Acid in H+, K+-ATPase/H. pylori Inhibition and Anti-Oxidative Mechanism 