Original Article

Inhibition of Cell Growth and Cellular Protein, DNA and RNA Synthesis in Human Hepatoma (HepG2) Cells by Ethanol Extract of Abnormal Savda Munziq of Traditional Uighur Medicine

Table 2

Pharmacological activities of plants from Uighur formula: ASMq.

PlantUsesPharmacological propertiesReference

BuglossEdible in Mediterranean dietRadical scavenging, inhibition of H2O2 and Fe2+-chelating activity in vitro[22]
Stomach ulcer in Middle EastProtective effect on ethanol-induced gastric ulcer in animals (root aqueous extract)[23]

Common fennelMedicinal and aromatic herb Antioxidant activity of methanolic extract [24]
Edible in Mediterranean diet Radical scavenging and iron-chelating activity in vitro[22]
Edible in Indian dietAntioxidant activity of aqueous extract (comparison with ascorbic acid)[25]
Digestive medicineTotal antioxidant, radical scavenging and metal chelating activities of aqueous and ethanol extracts[26]

Fragrant manjackEdible in IndiaNutritional value: high level of phosphorus[22]

JujubeAid digestion in ChinaImmunological activities: induced a rat spleen cells proliferation[27]

LicoriceStomachic and cough medicinein vitro and in vivo inhibition of Ehrlich ascites tumor cells proliferation (G. glabra)[28]
Inhibition of cell proliferation in the MCF-7 breast cancer cell line (G. uralensis ethanol extract)[29]
Inhibition of H2O2-induced apoptosis of lung fibroblastV79-4 cells (G. uralensis methanol extract)[30]
Antinephritis activity of licochalcone A (G. inflata)[31]
Prostate cancer cell growth inhibition of isoliquiritigenin[32]
Suppression of pulmonary metastasis by isoliquiritigenin[33]
Antitumoral effects similar to those of antimicrotubule agents of beta-hydroxy-DHP (G. glabra)[34]
Inhibition of lipid peroxidation (G. glabra)[35]
Isoliquiritigenin induced apoptosis in human gastric cancer MGC-803 cells[36]
Biphasic effect on the growth of breast tumor cell of glabridin and glabrene[37]
Licochalcone-A from G. glabra induced aptotosis of MCF-7 and HL-60 cell lines[38]
Protect DNA damage and decrease the stimulation of DNA repair synthesis by glycyrrhetinic acid[39]

LavenderFolk medicineAntioxidant activity (DPPH) of water extract[40]
Antiseptic usesStrong antimutagenic activity of essential oil (bacterial reverse mutation assay)[41]
Wound healingCytotoxicity of essential oil to human skin cells (in vitro)[42]
Iranian traditional medicineAnti-inflammatory activity of polyphenolic fraction and essential oil[43]
Turkish folk medicineNeuroprotective effect against glutamate toxicity (aqueous extract)[44]
Inflammatory diseasesInhibition of lipid peroxidation (phenolic compounds)[45]

Lemon BalmSedative, digestive medicineAntioxidant of the polar fraction (ethanolic extract, decoction)[40]
Folk medicineAntioxidant capacity (FRAP, DPPH, ABTS) of infusion[46]
Mediterranean dietAntioxidant activity (DPPH) of aqueous extract[47]
Bulgarian folk medicineAntioxidant activity (APTS) of infusion[48]
Herbal medicineOil cytotoxicity on cell lines A549, MCF-7, Caco-2, HL-60, K562 and B16F10[49]
Inflammatory diseasesInhibition of lipid peroxidation (phenolic compounds)[45]