Tylosema esculentum (Marama) Tuber and Bean Extracts Are Strong Antiviral Agents against Rotavirus Infection
Figure 4
Effect of coincubation of rotavirus with T. esculentum extracts on monolayer polarity (TER) (Ω/cm2) of H4 cells over time. Shown graphs of change in epithelial cell monolayer polarity exposed to extracts or AZT and rotavirus (treatment wells), extracts or AZT alone (control), or rotavirus alone (negative control) over time compared to respective controls. Tests were done in triplicate wells (12-well Transwell plates). MCE: T. esculentum bean cotyledon ethanolic extract (1 mg/mL), MSCE: T. esculentum bean husk ethanolic extract (0.1 mg/mL), MTW: T. esculentum tuber water extract (0.1 mg/mL), MSCW: T. esculentum bean husk water extract (0.01 mg/mL), MCW: T. esculentum bean cotyledon water extract (2 mg/mL), and AZT: Combivir (lamivudine and zidovudine) (0.75 mg/mL).
