Tylosema esculentum (Marama) Tuber and Bean Extracts Are Strong Antiviral Agents against Rotavirus Infection
Figure 6
T. esculentum extracts show direct inhibition of rotavirus infectivity on bovine intestinal epithelial cells (CIEB), pig intestinal epithelial cells (CLAB), and human intestinal epithelial cells (H4). Shown above are bars of % survival of epithelial cells {% change in cell viability after pre-exposure of rotavirus to T. esculentum extracts compared to rotavirus only wells at OD 595 nm ± % standard deviation}, respective levels of significance in terms of values (*). values were determined using Statsoft Statistica software (). Tests were done in triplicate wells. value between 0 and 5 (low level significance), value greater than 5, but less than 10 (middle level significance), and value greater than 10 (high level significance). MCE: T. esculentum bean cotyledon ethanolic extract, MSCE: T. esculentum bean husk ethanolic extract, MTW: T. esculentum tuber water extract, MSCW: T. esculentum bean husk water extract, MCW: T. esculentum bean cotyledon water extract, and AZT: Combivir (lamivudine and zidovudine).
