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Evidence-Based Complementary and Alternative Medicine
Volume 2011, Article ID 293060, 13 pages
http://dx.doi.org/10.1155/2011/293060
Research Article

Leea indica Ethyl Acetate Fraction Induces Growth-Inhibitory Effect in Various Cancer Cell Lines and Apoptosis in Ca Ski Human Cervical Epidermoid Carcinoma Cells

Biomolecular Research Group, Biochemistry Division, Institute of Biological Sciences, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia

Received 6 September 2010; Revised 12 December 2010; Accepted 11 January 2011

Copyright © 2011 Wong Yau Hsiung and Habsah Abdul Kadir. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [10 citations]

The following is the list of published articles that have cited the current article.

  • Nidyaletchmy Subba Reddy, Suerialoasan Navanesan, Saravana Kumar Sinniah, Norhanom Abdul Wahab, and Kae Shin Sim, “Phenolic content, antioxidant effect and cytotoxic activity of Leea indica leaves,” Bmc Complementary And Alternative Medicine, vol. 12, 2012. View at Publisher · View at Google Scholar
  • Yau Hsiung Wong, Habsah Abdul Kadir, and Sui Kiong Ling, “Bioassay-Guided Isolation of Cytotoxic Cycloartane Triterpenoid Glycosides from the Traditionally Used Medicinal Plant Leea indica,” Evidence-Based Complementary and Alternative Medicine, vol. 2012, pp. 1–11, 2012. View at Publisher · View at Google Scholar
  • Yau Hsiung Wong, and Habsah Abdul Kadir, “Induction of Mitochondria-Mediated Apoptosis in Ca Ski Human Cervical Cancer Cells Triggered by Mollic Acid Arabinoside Isolated from Leea indica,” Evidence-Based Complementary and Alternative Medicine, vol. 2012, pp. 1–11, 2012. View at Publisher · View at Google Scholar
  • Mohammad Mijanur Rahman, and Md. Asaduzzaman Khan, “Anti-cancer potential of South Asian plants,” Natural Products and Bioprospecting, vol. 3, no. 3, pp. 74–88, 2013. View at Publisher · View at Google Scholar
  • Annushuya Subba Reddy, Nurestri Abd Malek, Halijah Ibrahim, and Kae Shin Sim, “Cytotoxic effect of Alpinia scabra (Blume) Naves extracts on human breast and ovarian cancer cells,” Bmc Complementary and Alternative Medicine, vol. 13, 2013. View at Publisher · View at Google Scholar
  • A. Manjamalai, and V. M. Berlin Grace, “ The Chemotherapeutic Effect of Essential Oil of Plectranthus amboinicus (Lour) on Lung Metastasis Developed by B16F-10 Cell Line in C57BL/6 Mice ,” Cancer Investigation, vol. 31, no. 1, pp. 74–82, 2013. View at Publisher · View at Google Scholar
  • Md. Atiar Rahman, Talha bin Imran, and Shahidul Islam, “Antioxidative, antimicrobial and cytotoxic effects of the phenolics of Leea indica leaf extract,” Saudi Journal Of Biological Sciences, vol. 20, no. 3, pp. 213–225, 2013. View at Publisher · View at Google Scholar
  • Luciana Pereira Silva, Alisson Leonardo Matsuo, Ricardo Alexandre Azevedo, Carlos Rogério Figueiredo, João Henrique Guilardi Lago, Luiz Rodolpho Travassos, Regildo Márcio Gonçalves Silva, Natalia Girola, Felipe Valença Pereira, Elaine Guadelupe Rodrigues, Mariana Hiromi Massaoka, Aline Nogueira Rabaça, Camyla Fernandes Farias, and Natalia Silva Matias, “Antitumor activity of Kielmeyera coriacea leaf constituents in experimental melanoma, tested in vitro and in vivo in syngeneic mice,” Advanced Pharmaceutical Bulletin, vol. 4, no. 1, pp. 429–436, 2014. View at Publisher · View at Google Scholar
  • Yan Jiang, Hanjie Xu, and Jiafei Wang, “Alantolactone induces apoptosis of human cervical cancer cells via reactive oxygen species generation, glutathione depletion and inhibition of the Bcl-2/Bax signaling pathway,” Oncology Letters, vol. 11, no. 6, pp. 4203–4207, 2016. View at Publisher · View at Google Scholar
  • Temístocles Italo da Santana, Miria de Oliveira Barbosa, Paulo André Teixeira de Moraes Gomes, Anne Cecília Nascimento da Cruz, Teresinha Gonçalves da Silva, and Ana Cristina Lima Leite, “Synthesis, anticancer activity and mechanism of action of new thiazole derivatives,” European Journal of Medicinal Chemistry, 2017. View at Publisher · View at Google Scholar