Antispasmodic and Antidiarrheal Activities of Valeriana hardwickii Wall. Rhizome Are Putatively Mediated through Calcium Channel Blockade

Table 1

Effect of Valeriana hardwickii rhizome extract (Vh.Cr) on castor oil-induced diarrhea in mice.

Treatment (oral)	No. of mice/5 with diarrhea	% protection
Vehicle control (Saline 10 mL/kg)	0	—
Castor oil (10 mL/kg)	5	0
+ Vh.Cr (100 mg/kg)	4	20
+ Vh.Cr (300 mg/kg)	2*	60
+ Loperamide (10 mg/kg)	1*	80

* 𝑃<.05, compared to castor oil group, chi-square test.