In Vivo Effects of Cagaita (Eugenia dysenterica, DC.) Leaf Extracts on Diarrhea Treatment

Figure 7

Evaluation of hepatotoxicity in rats after oral administration of infusion, ethanolic and aqueous extract of E. dysenterica utilizing as parameters alterations in the levels of serum (U/L) alanine aminotransferase (ALT) enzyme. Values of mean and standard deviation of the effect exerted by the samples at different periods: no treatments (T0), after one dose (T1), seven-day dose (T2) and 14-day dose (T3). Negative control group received 1 mL of water and ricin oil (10 mg·kg^-1). Positive control group received loperamide (2 mg·kg^-1) and experimental groups received infusion and aqueous extract at the dose of 800 mg·kg^-1 and ethanolic extract at the dose of 400 mg·kg^-1. Vertical bars represent standard error. Asterisks indicate statistical difference from control (P  ≤  .05) by Dunnett test.