Aqueous Extract of Shi-Liu-Wei-Liu-Qi-Yin Induces G2/M Phase Arrest and Apoptosis in Human Bladder Carcinoma Cells via Fas and Mitochondrial Pathway
Figure 7
The effects of SLWLQY on the growth of TSGH-8301 cells in BALB/c nude mice. (a) TSGH-8301 cells were inoculated into nude mice and treated with SLWLQY (0.2, 0.5 and 1 g kg−1). The tumors were then dissected from nude mice at 4 weeks after vehicle or SLWLQY treatment. (b) Average tumor volumes of vehicle vs. SLWLQY-treated nude mice (n = 4) were measured at the end of experiment. (c) Western blot analyses were performed to determine the expression of Fas, FasL, Bax and Bcl2 proteins in the tumors. Four samples were analyzed in each group, and values represent the mean ± SD. Significance was accepted when P < .05. *P < .05 if compared with vehicle-treated mice.
