Toxicity and Neuropharmacological Effects of Elenine
Table 2
number of animals with loss of spontaneous movement, loss of muscle tone, and loss of righting reflex against the number of observations before and after 1, 2, and 3 h of treatment.
Loss of spontaneous movement
Loss of muscle tone
Loss of righting reflex
C
E-10
E-20
E-40
CHL
C
E-10
E-20
E-40
CHL
C
E-10
E-20
E-40
CHL
Before
0/10
0/10
0/10
0/10
0/10
0/10
0/10
0/10
0/10
0/10
0/10
0/10
0/10
0/10
0/10
1h
0/10
3/10*
6/10*
7/10*
8/10*
0/10
3/10*
4/10*
6/10*
7/10*
0/10
0/10
1/10
3/10*
3/10*
2h
0/10
4/10*
7/10*
8/10*
9/10*
0/10
4/10*
6/10*
7/10*
8/10*
0/10
0/10
1/10
3/10*
3/10*
3h
0/10
4/10*
7/10*
8/10*
9/10*
0/10
6/10*
6/10*
7/10*
8/10*
0/10
0/10
1/10
3/10*
3/10*
(a) C, control, 10, 20, and 40 mg/Kg elenine; CHL, chlorpromazine 10 g/Kg. * versus control group.
