Research Article

Cattle Bile Aggravates Diclofenac Sodium-Induced Small Intestinal Injury in Mice

Figure 5

Effect of CB administration on contents of bile acids in small intestine. Mice fed the control or CB diet were treated with DIF or vehicle and the contents of bile acids in the small intestine were determined by HPLC. Columns and bars represent the mean and SEM of 3 to 6 mice in each group. Statistical analysis was carried out by two-way ANOVA. CB treatment significantly changed both TMCA and TCA contents in the small intestine (two-way ANOVA, ). DIF treatment significantly changed TCA content ( ) but not TMCA ( ) content in the small intestine. Interaction between DIF treatment and CB administration was not significant ( ) in terms of both TMCA and TCA contents in the small intestine.
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