Toxicity Profile of the Aqueous Ethanol Root Extract of Corrigiola telephiifolia Pourr. (Caryophyllaceae) in Rodents
Table 5
Effect of a forty-day oral administration of Corrigiola telephiifolia extract on biochemical parameters of female Wistar rats.
Corrigiola telephiifolia (mg/kg/day)
Control
5
70
2000
Parameter
Na mmol/L
149.4 ± 0.7
148.0 ± 0.5
141.6 ± 1.0*
136.1 ± 1.
Cl mmol/L
117.3 ± 0.5
116.4 ± 0.3
110.1 ± 0.7*
106.3 ± 1.
K mmol/L
8.5 ± 0.5
8.2 ± 0.6
7.8 ± 0.5
9.3 ± 0.9
Mg mmol/L
1.6 ± 0.2
1.5 ± 0.2
1.5 ± 0.1
1.4 ± 0.1
Ca mmol/L
2.2 ± 0.2
2.1 ± 0.2
2.0 ± 0.1
2.0 ± 0.1
Iron mol/L
51.6 ± 4.4
52.3 ± 3.7
53.6 ± 2.8
46.7 ± 4.0
Ph.org mmol/L
3.2 ± 0.2
3.3 ± 0.4
3.8 ± 0.5
4.3 ± 0.
Total Protein g/L
75.4 ± 1.0
74.1 ± 1.2
70.9 ± 2.0
69.1 ± 1.
Glucose mmol/L
8.0 ± 1.0
7.5 ± 0.8
6.7 ± 0.5
6.4 ± 1.0
Urea mmol/L
6.6 ± 0.2
6.3 ± 0.5
5.6 ± 0.5
6.0 ± 0.4
Creatinine mol/L
26.4 ± 5.1
25.7 ± 1.3
22.9 ± 1.2
87.0 ± 15.
Bicarbonates mm Hg
16.0 ± 1.8
15.4 ± 1.1
14.0 ± 1.5
20.9 ± 2.1
Uric acid mol/L
194.5 ± 59.7
183.7 ± 35.2
177.3 ± 43.6
175.6 ± 50.1
Total cholesterol mmol/L
1.7 ± 0.1
1.7 ± 0.1
1.6 ± 0.1
1.4 ± 0.1
Triglycerides mmol/L
1.8 ± 0.3
1.7 ± 0.2
1.7 ± 0.2
1.3 ± 0.3
Bilirubin mol/L
25.4 ± 2.5
25.0 ± 2.4
24.4 ± 2.1
27.4 ± 2.9
AST UI/L
54.5 ± 6.1
55.1 ± 6.0
57.7 ± 6.2
78.5 ± 21.8
ALT UI/L
20.2 ± 1.7
21.3 ± 2.5
27.1 ± 5.0
33.7 ± 8.6
ALP UI/L
121.7 ± 10.8
115.9 ± 7.5
103.0 ± 9.9
202.1 ± 30.
GGT UI/L
1.4 ± 0.1
1.4 ± 0.2
1.5 ± 0.2
1.9 ± 0.
C. telephiifolia extract was administered daily for 40 consecutive days to rats Data are expressed as mean ± S.E.M. ignificantly different from the control
