Toxicity Profile of the Aqueous Ethanol Root Extract of Corrigiola telephiifolia Pourr. (Caryophyllaceae) in Rodents
Table 7
Effect of a forty-day oral administration of Corrigiola telephiifolia extract on relative organ weights of Wistar rats.
Corrigiola telephiifolia (mg/kg/day)
Control
5
70
2000
Females
Organ
Heart
0.31 ± 0.02
0.30 ± 0.03
0.28 ± 0.02
0.31 ± 0.05
Liver
2.20 ± 0.12
2.25 ± 0.10
2.28 ± 0.10
2.35 ± 0.10
Spleen
0.26 ± 0.03
0.25 ± 0.01
0.21 ± 0.01
0.22 ± 0.03
Stomach
0.65 ± 0.10
0.64 ± 0.08
0.63 ± 0.10
0.68 ± 0.09
Right lung
0.29 ± 0.03
0.3 ± 0.04
0.30 ± 0.03
0.39 ± 0.10
Left lung
0.24 ± 0.04
0.23 ± 0.03
0.22 ± 0.02
0.27 ± 0.07
Right kidney
0.31 ± 0.02
0.30 ± 0.02
0.25 ± 0.02
0.29 ± 0.04
Left kidney
0.29 ± 0.01
0.28 ± 0.01
0.26 ± 0.01
0.28 ± 0.04
Males
Organ
Heart
0.32 ± 0.01
0.33 ± 0.01
0.35 ± 0.05
0.30 ± 0.01
Liver
2.60 ± 0.12
2.70 ± 0.14
2.79 ± 0.16
2.76 ± 0.18
Spleen
0.23 ±0.01
0.22 ± 0.01
0.21 ± 0.01
0.22 ± 0.01
Stomach
0.63 ± 0.04
0.64 ± 0.04
0.66 ± 0.04
0.73 ± 0.05
Right lung
0.30 ± 0.01
0.30 ± 0.02
0.30 ± 0.03
0.31 ± 0.02
Left lung
0.22 ± 0.01
0.22 ± 0.01
0.20 ± 0.01
0.21 ± 0.02
Right kidney
0.30 ± 0.01
0.29 ± 0.01
0.28 ± 0.02
0.31 ± 0.01
Left kidney
0.28 ± 0.01
0.29 ± 0.01
0.27 ± 0.02
0.30 ± 0.01
C. telephiifolia extract was administered daily for 40 consecutive days to rats Data are expressed as mean ± S.E.M. There were no statistically significant differences in the relative organ weights.
