Administration of a Decoction of Sucrose- and Polysaccharide-Rich Radix Astragali (Huang Qi) Ameliorated Insulin Resistance and Fatty Liver but Affected Beta-Cell Function in Type 2 Diabetic Rats
Figure 2
Therapeutic efficacy of the water extract of Radix Astragali (AM-W) for type 2 diabetes (T2D). Once induced T2D rats were identified, the following biochemical parameters were evaluated before and after 2 months of AM-W treatment. (a) Body weight (g); (b) fasting blood sugar (mg/dL); (c) intravenous glucose tolerance test (IVGTT) for which results were calculated as the area under the curve (AUC); (d) the insulin resistance index for which results are presented as HOMA-IR; (e) beta-cell function index for which results are presented as HOMA-IR; (f) fasting serum insulin (ng/mL). Differences were determined by ANOVA followed by the Tukey-Kramer test. For body weight, * was considered significant when compared to the body weight before AM-W treatment. For the remaining parameters, * compared to the nondiabetic group (ND) and ∆ for the comparison between T2D and T2D + AM-W (500 mg/kg) rats.
