Screening Antitumor Compounds Psoralen and Isopsoralen from Psoralea corylifolia L. Seeds
Figure 4
The inhibition ability of psoralen (a) and isopsoralen (b) on proliferation of four tumor cells. The cells were incubated with vincristine sulfate or doxorubicin hydrochloride and different concentrations of psoralen and isopsoralen for 48 h. Incubation with DMSO alone as control and the final concentration of DMSO in the medium never exceeded 0.1%. After 48 h, the MTT assay was performed to measure cell inhibition rate. Results are expressed as means ± SD of four separate experiments for each data point. Significant difference was set at .95.
