Total Flavonoids Extracted from Xiaobuxin-Tang on the Hyperactivity of Hypothalamic-Pituitary-Adrenal Axis in Chronically Stressed Rats

Figure 4

Effect of XBXT-2 on hippocampal GRs expression in chronically stressed rats. The intensity of western bands was quantified with a densitometric scanner. Each column represents as the mean ± SEM, n = 5. Band 1: control + vehicle; Band 2: stress + vehicle; Band 3: stress + IMI (10 mg/kg, p.o.); Band 4: stress + XBXT-2 (25 mg/kg, p.o.); Band 5: stress + XBXT-2 (50 mg/kg, p.o.); ***P < .001 compared with control-vehicle, ^##P < .01 compared with stress-vehicle (ANOVA followed by Newmann-Kuels tests).