Ginseng (Panax quinquefolius) and Licorice (Glycyrrhiza uralensis) Root Extract Combinations Increase Hepatocarcinoma Cell (Hep-G2) Viability

Table 2

Cell-cycle analysis.

Cell cycle	Sub G1		G1		S		G2/M
Time (h) 24
Control	0.46 ± 0.27	a	63.19 ± 0.83	a	14.10 ± 0.51	b	20.08 ± 0.83	a
GE	2.05 ± 2.21	a	68.18 ± 5.30	ab	9.39 ± 2.52	ab	19.61 ± 3.39	a
LE	0.79 ± 0.26	a	73.4 ± 2.50	bc	9.54 ± 1.55	ab	15.52 ± 1.76	a
f1/5	0.46 ± 0.05	a	75.01 ± 1.50	bc	9.74 ± 1.87	ab	14.07 ± 2.08	a
f1/3	0.26 ± 0.08	a	76.21 ± 2.01	bc	8.04 ± 1.92	a	14.63 ± 2.50	a
f1/2	0.25 ± 0.03	a	77.34 ± 2.59	c	8.18 ± 2.65	a	13.93 ± 3.01	a
f2/3	0.27 ± 0.01	a	76.86 ± 3.55	bc	8.54 ± 0.47	a	13.76 ± 2.85	a
f4/5	0.31 ± 0.06	a	77.37 ± 4.24	c	7.75 ± 2.42	a	14.12 ± 3.73	a
Time (h) 48
Control	0.40 ± 0.36	a	69.61 ± 0.85	a	10.54 ± 3.09	a	17.74 ± 3.47	b
GE	0.97 ± 0.21	b	77.31 ± 1.76	b	6.86 ± 2.25	a	14.17 ± 1.47	ab
LE	0.67 ± 0.11	ab	78.47 ± 0.65	bc	8.88 ± 1.47	a	11.79 ± 1.63	ab
f1/5	0.32 ± 0.08	a	80.38 ± 0.73	bcd	6.72 ± 2.22	a	12.29 ± 2.86	ab
f1/3	0.31 ± 0.02	a	82.48 ± 1.56	cd	6.27 ± 2.53	a	10.8 ± 1.63	a
f1/2	0.26 ± 0.16	a	82.92 ± 1.76	d	5.76 ± 2.06	a	10.84 ± 2.89	a
f2/3	0.29 ± 0.13	a	83.17 ± 1.77	d	5.08 ± 1.21	a	11.20 ± 0.96	a
f4/5	0.35 ± 0.14	a	82.39 ± 2.11	cd	5.36 ± 1.31	a	11.45 ± 1.19	a
Time (h) 72
Control	0.54 ± 0.12	a	65.76 ± 2.02	a	10.38 ± 4.60	a	20.17 ± 2.14	c
GE	1.14 ± 0.27	c	75.73 ± 0.61	c	6.10 ± 2.87	a	16.15 ± 2.83	bc
LE	1.04 ± 0.11	bc	79.44 ± 0.62	bc	8.71 ± 0.70	a	10.90 ± 0.63	ab
f1/5	0.69 ± 0.23	abc	80.68 ± 0.24	abc	6.80 ± 3.04	a	11.91 ± 2.55	ab
f1/3	0.73 ± 0.16	abc	81.68 ± 0.62	abc	5.95 ± 2.47	a	11.60 ± 2.36	ab
f1/2	0.63 ± 0.02	ab	83.27 ± 1.07	ab	4.77 ± 2.04	a	11.16 ± 1.44	ab
f2/3	0.45 ± 0.12	a	82.93 ± 0.22	a	6.55 ± 2.69	a	9.87 ± 2.12	ab
f4/5	0.42 ± 0.19	a	79.31 ± 1.50	a	7.98 ± 2.74	a	11.82 ± 1.39	ab

Columns of the same category and time period with different letters are significantly different (𝑃<.05).