Original Article

San-Huang-Xie-Xin-Tang Protects against Activated Microglia- and 6-OHDA-Induced Toxicity in Neuronal SH-SY5Y Cells

Figure 3

Effects of SHXT on the IκBα expression (a) and NF-κB activation (b) in lipopolysaccharide (LPS, 100 ng/mL)-treated BV-2 cells. Cultures were pretreated with SHXT for 30 min before the addition of LPS. Then the cells were collected at 1 h for NF-κB activity assay and at 24 h for IκBα protein analyses. Densitometry analyses are presented as the relative ratio of protein/β-actin protein, and they are represented as percentages of the control group. Changes of NF-κBp65 translocation levels are represented as percentages of the control group. Bars represent the mean ± SEM from six independent experiments. #P <  .05 versus control, *P <  .05 versus LPS only.
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429384.fig.003b
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