Dietary Phenethyl Isothiocyanate Alters Gene Expression in Human Breast Cancer Cells

Table 2

Significantly changed genes following treatment with 3 𝜇M of PEITC (n = 4, ^∗𝑃<.05, ^∗∗∗𝑃<.001). Results are expressed as fold change as compared to vehicle controls and represent the average of five independent microarray experiments.

Gene name	Description	Fold ± S.D.
p57	cyclin-dependent kinase inhibitor 1C	5.23*± 2.74
CYP19	cytochrome P450, subfamily XIX	5.22***± 0.988
BRCA2	Breast Cancer 2, early-onset	4.22*± 2.30
IL-2	Interleukin-2, T-cell growth factor	3.16*± 1.22
ATF2	Activating Transcription Factor 2	2.60*± 0.900
p53	Tumor protein p53	2.12*± 1.46
Hsp27	Heat shock 27 KD protein	1.84*± 0.409