Cranberry and Grape Seed Extracts Inhibit the Proliferative Phenotype of Oral Squamous Cell Carcinomas
Figure 8
Effects of CE and GSE on cell morphology in 30-min adhesion assays. SCC25 ((a–c)) and CAL27 ((d–f)) cells from adhesion assays were fixed with formalin and stained with crystal violet. Analysis of captured images revealed that SCC25 cell morphology (a) was significantly altered and cell clustering (cc) increased by the administration of CE (b) and GSE (c) at GIMAX concentrations (50, 80 μg/ml, resp.) where cells were present; although significant areas of each experimental well (CE, GSE) had few, if any, adherent cells. CAL27 cells (d) exhibited no notable differences in cell clustering or cell–cell adhesion under CE (e) or GSE (f) administration. A colour version of this figure is available online as supplementary data.
