Original Article

REC-2006—A Fractionated Extract of Podophyllum hexandrum Protects Cellular DNA from Radiation-Induced Damage by Reducing the Initial Damage and Enhancing Its Repair In Vivo

Figure 3

(a) Effect of REC-2006 on radiation DNA damage and repair in mouse thymocytes. Lane 1, PCR products from mice without any treatment; lanes 2–4, amplification product from mice exposed to 10 Gy and killed at 0, 15 and 60 min, respectively; lanes 5–7 amplification product from REC-2006 pretreated irradiated mice taken at 0, 15 and 60 min, respectively. (b) Quantitative estimation of effect of REC-2006 on repair kinetics of -globin gene in mice in vivo. Graph shows the percent amplification of -globin in the absence or presence of REC-2006 at 0, 15 and 60 min after 10 Gy irradiation to mice.
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(a)
473953.fig.003b
(b)